Molecular mechanisms of fentanyl mediated β-arrestin biased signaling

The development of novel analgesics with improved safety profiles to combat the opioid epidemic represents a central question to G protein coupled receptor structural biology and pharmacology: What chemical features dictate G protein or β-arrestin signaling? Here we use adaptively biased molecular d...

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Detalles Bibliográficos
Autores principales: de Waal, Parker W., Shi, Jingjing, You, Erli, Wang, Xiaoxi, Melcher, Karsten, Jiang, Yi, Xu, H. Eric, Dickson, Bradley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176292/
https://www.ncbi.nlm.nih.gov/pubmed/32275713
http://dx.doi.org/10.1371/journal.pcbi.1007394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176292/
https://www.ncbi.nlm.nih.gov/pubmed/32275713
http://dx.doi.org/10.1371/journal.pcbi.1007394

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