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Assessing heterogeneity among single embryos and single blastomeres using open microfluidic design

The process by which a zygote develops from a single cell into a multicellular organism is poorly understood. Advances are hindered by detection specificity and sensitivity limitations of single-cell protein tools and by challenges in integrating multimodal data. We introduce an open microfluidic to...

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Detalles Bibliográficos
Autores principales: Rosàs-Canyelles, Elisabet, Modzelewski, Andrew J., Geldert, Alisha, He, Lin, Herr, Amy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176412/
https://www.ncbi.nlm.nih.gov/pubmed/32494630
http://dx.doi.org/10.1126/sciadv.aay1751