A potent CBP/p300-Snail interaction inhibitor suppresses tumor growth and metastasis in wild-type p53-expressing cancer

The zinc finger transcription factor Snail is aberrantly activated in many human cancers and associated with poor prognosis. Therefore, targeting Snail is expected to exert therapeutic benefit in patients with cancer. However, Snail has traditionally been considered “undruggable,” and no effective p...

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Detalles Bibliográficos
Autores principales: Li, Hong-Mei, Bi, Yan-Ran, Li, Yang, Fu, Rong, Lv, Wen-Cong, Jiang, Nan, Xu, Ying, Ren, Bo-Xue, Chen, Ya-Dong, Xie, Hui, Wang, Shui, Lu, Tao, Wu, Zhao-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176418/
https://www.ncbi.nlm.nih.gov/pubmed/32494626
http://dx.doi.org/10.1126/sciadv.aaw8500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176418/
https://www.ncbi.nlm.nih.gov/pubmed/32494626
http://dx.doi.org/10.1126/sciadv.aaw8500

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