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Smoothened agonist sterosome immobilized hybrid scaffold for bone regeneration

Biomaterial delivery of bioactive agents and manipulation of stem cell fate are an attractive approach to promote tissue regeneration. Here, smoothened agonist sterosome is developed using small-molecule activators [20S-hydroxycholesterol (OHC) and purmorphamine (PUR)] of the smoothened protein in t...

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Detalles Bibliográficos
Autores principales: Lee, Chung-Sung, Kim, Soyon, Fan, Jiabing, Hwang, Hee Sook, Aghaloo, Tara, Lee, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176430/
https://www.ncbi.nlm.nih.gov/pubmed/32494652
http://dx.doi.org/10.1126/sciadv.aaz7822