Single-molecule functional anatomy of endogenous HER2-HER3 heterodimers

Human epidermal growth factor receptors (HERs) are the primary targets of many directed cancer therapies. However, the reason a specific dimer of HERs generates a stronger proliferative signal than other permutations remains unclear. Here, we used single-molecule immunoprecipitation to develop a bio...

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Detalles Bibliográficos
Autores principales: Choi, Byoungsan, Cha, Minkwon, Eun, Gee Sung, Lee, Dae Hee, Lee, Seul, Ehsan, Muhammad, Chae, Pil Seok, Heo, Won Do, Park, YongKeun, Yoon, Tae-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176432/
https://www.ncbi.nlm.nih.gov/pubmed/32267234
http://dx.doi.org/10.7554/eLife.53934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176432/
https://www.ncbi.nlm.nih.gov/pubmed/32267234
http://dx.doi.org/10.7554/eLife.53934

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