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Structural basis for ion selectivity in TMEM175 K(+) channels
The TMEM175 family constitutes recently discovered K(+)channels that are important for autophagosome turnover and lysosomal pH regulation and are associated with the early onset of Parkinson Disease. TMEM175 channels lack a P-loop selectivity filter, a hallmark of all known K(+) channels, raising th...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176437/ https://www.ncbi.nlm.nih.gov/pubmed/32267231 http://dx.doi.org/10.7554/eLife.53683 |