Sinomenine Inhibits Non-Small Cell Lung Cancer via Downregulation of Hexokinases II-Mediated Aerobic Glycolysis

BACKGROUND: Addiction to aerobic glycolysis is a common metabolic phenotype in human non-small cell lung cancer (NSCLC). The natural product Sinomenine (Sin) exhibits significant anti-tumor effects in various human cancers. However, the underlying mechanism remains elusive. METHODS: The inhibitory e...

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Detalles Bibliográficos
Autores principales: Liu, Wenbin, Yu, Xinfang, Zhou, Li, Li, Jigang, Li, Ming, Li, Wei, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176511/
https://www.ncbi.nlm.nih.gov/pubmed/32368080
http://dx.doi.org/10.2147/OTT.S243212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176511/
https://www.ncbi.nlm.nih.gov/pubmed/32368080
http://dx.doi.org/10.2147/OTT.S243212

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