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A high definition picture of somatic mutations in chronic lymphoproliferative disorder of natural killer cells

The molecular pathogenesis of chronic lymphoproliferative disorder of natural killer (NK) cells (CLPD‐NK) is poorly understood. Following the screening of 57 CLPD-NK patients, only five presented STAT3 mutations. WES profiling of 13 cases negative for STAT3/STAT5B mutations uncovered an average of 1...

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Detalles Bibliográficos
Autores principales: Gasparini, Vanessa Rebecca, Binatti, Andrea, Coppe, Alessandro, Teramo, Antonella, Vicenzetto, Cristina, Calabretto, Giulia, Barilà, Gregorio, Barizza, Annica, Giussani, Edoardo, Facco, Monica, Mustjoki, Satu, Semenzato, Gianpietro, Zambello, Renato, Bortoluzzi, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176632/
https://www.ncbi.nlm.nih.gov/pubmed/32321919
http://dx.doi.org/10.1038/s41408-020-0309-2