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Store-operated Ca(2+) entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migration

Stromal interaction molecules (STIM1, 2) are acting as sensors for Ca(2+) in intracellular stores and activate Orai channels at the plasma membrane for store-operated Ca(2+) entry (SOCE), while classical transient receptor potential (TRPC) channel mediate receptor-operated Ca(2+) entry (ROCE). Sever...

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Detalles Bibliográficos
Autores principales: Bendiks, Larissa, Geiger, Fabienne, Gudermann, Thomas, Feske, Stefan, Dietrich, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176639/
https://www.ncbi.nlm.nih.gov/pubmed/32321939
http://dx.doi.org/10.1038/s41598-020-63677-2