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Possibility of cancer-stem-cell-targeted radioimmunotherapy for acute myelogenous leukemia using (211)At-CXCR4 monoclonal antibody
To explore stem-cell-targeted radioimmunotherapy with α-particles in acute myelogenous leukemia (AML), pharmacokinetics and dosimetry of the (211)At-labeled anti-C-X-C chemokine receptor type 4 monoclonal antibody ((211)At-CXCR4 mAb) were conducted using tumor xenografted mice. The biological half-l...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176675/ https://www.ncbi.nlm.nih.gov/pubmed/32321944 http://dx.doi.org/10.1038/s41598-020-63557-9 |