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A non-anhydrous, minimally basic protocol for the simplification of nucleophilic (18)F-fluorination chemistry

Fluorine-18 radiolabeling typically includes several conserved steps including elution of the [(18)F]fluoride from an anion exchange cartridge with a basic solution of K(2)CO(3) or KHCO(3) and Kryptofix 2.2.2. in mixture of acetonitrile and water followed by rigorous azeotropic drying to remove the...

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Detalles Bibliográficos
Autores principales: Inkster, J. A. H., Akurathi, V., Sromek, A. W., Chen, Y., Neumeyer, J. L., Packard, A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176689/
https://www.ncbi.nlm.nih.gov/pubmed/32321927
http://dx.doi.org/10.1038/s41598-020-61845-y