The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced acute liver failure

Acetaminophen (APAP) is the main cause of acute liver failure in the West. Specific efficacious therapies for acute liver failure (ALF) are limited and time-dependent. The mechanisms that drive irreversible acute liver failure remain poorly characterized. Here we report that the recently discovered...

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Detalles Bibliográficos
Autores principales: Chauhan, Abhishek, Sheriff, Lozan, Hussain, Mohammed T., Webb, Gwilym J., Patten, Daniel A., Shepherd, Emma L., Shaw, Robert, Weston, Christopher J., Haldar, Debashis, Bourke, Samuel, Bhandari, Rajan, Watson, Stephanie, Adams, David H., Watson, Steve P., Lalor, Patricia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176690/
https://www.ncbi.nlm.nih.gov/pubmed/32321925
http://dx.doi.org/10.1038/s41467-020-15584-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176690/
https://www.ncbi.nlm.nih.gov/pubmed/32321925
http://dx.doi.org/10.1038/s41467-020-15584-3

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