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CD8(+) regulatory T cells are critical in prevention of autoimmune-mediated diabetes

Type 1 diabetes (T1D) is an autoimmune disease in which insulin-producing pancreatic β-cells are destroyed. Intestinal helminths can cause asymptomatic chronic and immunosuppressive infections and suppress disease in rodent models of T1D. However, the underlying regulatory mechanisms for this protec...

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Detalles Bibliográficos
Autores principales: Shimokawa, Chikako, Kato, Tamotsu, Takeuchi, Tadashi, Ohshima, Noriyasu, Furuki, Takao, Ohtsu, Yoshiaki, Suzue, Kazutomo, Imai, Takashi, Obi, Seiji, Olia, Alex, Izumi, Takashi, Sakurai, Minoru, Arakawa, Hirokazu, Ohno, Hiroshi, Hisaeda, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176710/
https://www.ncbi.nlm.nih.gov/pubmed/32321922
http://dx.doi.org/10.1038/s41467-020-15857-x