Cargando…

Acute-on-chronic liver failure alters meropenem pharmacokinetics in critically ill patients with continuous hemodialysis: an observational study

BACKGROUND: Infection and sepsis are a main cause of acute-on-chronic liver failure (ACLF). Adequate dosing of antimicrobial therapy is of central importance to improve outcome. Liver failure may alter antibiotic drug concentrations via changes of drug distribution and elimination. We studied the ph...

Descripción completa

Detalles Bibliográficos
Autores principales: Grensemann, Jörn, Busse, David, König, Christina, Roedl, Kevin, Jäger, Walter, Jarczak, Dominik, Iwersen-Bergmann, Stefanie, Manthey, Carolin, Kluge, Stefan, Kloft, Charlotte, Fuhrmann, Valentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176801/
https://www.ncbi.nlm.nih.gov/pubmed/32323030
http://dx.doi.org/10.1186/s13613-020-00666-8