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Osthole stimulates bone formation, drives vascularization and retards adipogenesis to alleviate alcohol‐induced osteonecrosis of the femoral head

Characteristic pathological changes in osteonecrosis of the femoral head (ONFH) include reduced osteogenic differentiation of bone mesenchymal stem cells (BMSCs), impaired osseous circulation and increased intramedullary adipocytes deposition. Osthole is a bioactive derivative from coumarin with a w...

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Detalles Bibliográficos
Autores principales: Yu, Hongping, Zhu, Daoyu, Liu, Pei, Yang, Qianhao, Gao, Junjie, Huang, Yigang, Chen, Yixuan, Gao, Youshui, Zhang, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176840/
https://www.ncbi.nlm.nih.gov/pubmed/32135036
http://dx.doi.org/10.1111/jcmm.15103