Inhibition of PHLPP1 ameliorates cardiac dysfunction via activation of the PI3K/Akt/mTOR signalling pathway in diabetic cardiomyopathy

BACKGROUND: Pleckstrin homology (PH) domain leucine‐rich repeat protein phosphatase 1 (PHLPP1) is a kind of serine/threonine phosphatase, whose dysregulation is accompanied with numerous human diseases. However, its role in diabetic cardiomyopathy remains unclear. We explored the underlying function...

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Detalles Bibliográficos
Autores principales: Zhang, Mingjun, Wang, Xuyang, Liu, Ming, Liu, Dian, Pan, Jinyu, Tian, Jingjing, Jin, Tao, Xu, Yunfan, An, Fengshuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176843/
https://www.ncbi.nlm.nih.gov/pubmed/32150791
http://dx.doi.org/10.1111/jcmm.15123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176843/
https://www.ncbi.nlm.nih.gov/pubmed/32150791
http://dx.doi.org/10.1111/jcmm.15123

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