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MiR‐3116 sensitizes glioma cells to temozolomide by targeting FGFR1 and regulating the FGFR1/PI3K/AKT pathway

Glioma is a brain tumour that is often diagnosed, and temozolomide (TMZ) is a common chemotherapeutic drug used in glioma. Yet, resistance to TMZ is a chief hurdle towards curing the malignancy. The current work explores the pathways and involvement of miR‐3116 in the TMZ resistance. miR‐3116 and FG...

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Detalles Bibliográficos
Autores principales: Kong, Shiqi, Cao, Yingxiao, Li, Xin, Li, Zhenzhong, Xin, Yuling, Meng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176860/
https://www.ncbi.nlm.nih.gov/pubmed/32181582
http://dx.doi.org/10.1111/jcmm.15133