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Knockout of AKAP150 improves impaired BK channel‐mediated vascular dysfunction through the Akt/GSK3β signalling pathway in diabetes mellitus

Vascular dysfunction resulting from diabetes is an important factor in arteriosclerosis. Previous studies have shown that during hyperglycaemia and diabetes, AKAP150 promotes vascular tone enhancement by intensifying the remodelling of the BK channel. However, the interaction between AKAP150 and the...

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Detalles Bibliográficos
Autores principales: Zhu, Yan‐Rong, Jiang, Xiao‐Xin, Ye, Peng, Wang, Zhi‐Mei, Zheng, Yaguo, Liu, Zhizhong, Chen, Shao‐Liang, Zhang, Dai‐Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176888/
https://www.ncbi.nlm.nih.gov/pubmed/32163656
http://dx.doi.org/10.1111/jcmm.15143