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miR‐152‐5p suppresses glioma progression and tumorigenesis and potentiates temozolomide sensitivity by targeting FBXL7

A generally used chemotherapeutic drug for glioma, a frequently diagnosed brain tumour, is temozolomide (TMZ). Our study investigated the activity of FBXL7 and miR‐152‐5p in glioma. Levels of microRNA‐152‐5p (miR‐152‐5p) and the transcript and protein of FBXL7 were assessed by real‐time PCR and West...

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Detalles Bibliográficos
Autores principales: Kong, Shiqi, Fang, Yanwei, Wang, Bingqian, Cao, Yingxiao, He, Runzhi, Zhao, Zongmao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176889/
https://www.ncbi.nlm.nih.gov/pubmed/32150671
http://dx.doi.org/10.1111/jcmm.15114