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Myricetin Possesses Anthelmintic Activity and Attenuates Hepatic Fibrosis via Modulating TGFβ1 and Akt Signaling and Shifting Th1/Th2 Balance in Schistosoma japonicum-Infected Mice

Schistosomiasis is a zoonotic and debilitating parasitic disease caused by Schistosoma japonicum. Praziquantel remains the choice for treating schistosomiasis, but its efficacy could be hampered by emergence of resistance. In this study, using large-scale drug screening, we selected out myricetin, a...

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Detalles Bibliográficos
Autores principales: Huang, Ping, Zhou, Minyu, Cheng, Shaoyun, Hu, Yue, Gao, Minzhao, Ma, Yubin, Limpanont, Yanin, Zhou, Hongli, Dekumyoy, Paron, Cheng, Yixin, Lv, Zhiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176910/
https://www.ncbi.nlm.nih.gov/pubmed/32373112
http://dx.doi.org/10.3389/fimmu.2020.00593