Difluoromethylornithine, a Decarboxylase 1 Inhibitor, Suppresses Hepatitis B Virus Replication by Reducing HBc Protein Levels

Current treatments of hepatitis B virus (HBV) are limited to Interferon-alpha or the nucleos(t)ide analogs antiviral therapies, and it is crucial to develop and define new antiviral drugs to cure HBV. In this study, we explored the anti-HBV effect of difluoromethylornithine (DFMO), an irreversibly i...

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Detalles Bibliográficos
Autores principales: Mao, Binli, Wang, Zhuo, Pi, Sidie, Long, Quanxin, Chen, Ke, Cui, Jing, Huang, Ailong, Hu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176913/
https://www.ncbi.nlm.nih.gov/pubmed/32373551
http://dx.doi.org/10.3389/fcimb.2020.00158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176913/
https://www.ncbi.nlm.nih.gov/pubmed/32373551
http://dx.doi.org/10.3389/fcimb.2020.00158

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