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Towards the total synthesis of chondrochloren A: synthesis of the (Z)-enamide fragment
The stereoselective synthesis of the (Z)-enamide fragment of chondrochloren (1) is described. A Buchwald-type coupling between amide 3 and (Z)-bromide 4 was used to generate the required fragment. The employed amide 3 comprising three chiral centers was obtained through a seven-step sequence startin...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176928/ https://www.ncbi.nlm.nih.gov/pubmed/32362944 http://dx.doi.org/10.3762/bjoc.16.64 |