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Apatinib Combined with Local Irradiation Leads to Systemic Tumor Control via Reversal of Immunosuppressive Tumor Microenvironment in Lung Cancer

PURPOSE: This study aimed to investigate the potential systemic antitumor effects of stereotactic ablative radiotherapy (SABR) and apatinib (a novel vascular endothelial growth factor receptor 2 inhibitor) via reversing the immunosuppressive tumor microenvironment for lung carcinoma. MATERIALS AND M...

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Detalles Bibliográficos
Autores principales: Liang, Li-jun, Hu, Chen-xi, Wen, Yi-xuan, Geng, Xiao-wei, Chen, Ting, Gu, Guo-qing, Wang, Lei, Xia, You-you, Liu, Yong, Fei, Jia-yan, Dong, Jie, Zhao, Feng-hua, Ahongjiang, Yiliyar, Hui, Kai-yuan, Jiang, Xiao-dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176950/
https://www.ncbi.nlm.nih.gov/pubmed/31476848
http://dx.doi.org/10.4143/crt.2019.296