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Modulation of Nrf2 by quercetin in doxorubicin-treated rats

Doxorubicin (DOXO), a potent and widely used chemotherapeutic agent, causes irreversible heart failure by increasing oxidative stress, which limits its clinical utility. Nuclear factor erythroid-derived 2 -like 2 (Nrf2) is a prominent central regulator of cellular impenetrable to oxidants. The purpo...

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Detalles Bibliográficos
Autores principales: Sharma, Anish, Parikh, Mihir, Shah, Hital, Gandhi, Tejal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177035/
https://www.ncbi.nlm.nih.gov/pubmed/32337383
http://dx.doi.org/10.1016/j.heliyon.2020.e03803