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Sirt4: A Multifaceted Enzyme at the Crossroads of Mitochondrial Metabolism and Cancer
Sirtuins are NAD(+)-dependent deacylases that play crucial roles in the regulation of cellular metabolism, and as a result, are implicated in several diseases. The mitochondrial sirtuin Sirt4, for a long time considered as mainly a mono-ADP-ribosyltransferase, recently has shown a robust deacylase a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177044/ https://www.ncbi.nlm.nih.gov/pubmed/32373514 http://dx.doi.org/10.3389/fonc.2020.00474 |