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Sirt4: A Multifaceted Enzyme at the Crossroads of Mitochondrial Metabolism and Cancer

Sirtuins are NAD(+)-dependent deacylases that play crucial roles in the regulation of cellular metabolism, and as a result, are implicated in several diseases. The mitochondrial sirtuin Sirt4, for a long time considered as mainly a mono-ADP-ribosyltransferase, recently has shown a robust deacylase a...

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Detalles Bibliográficos
Autores principales:	Tomaselli, Daniela, Steegborn, Clemens, Mai, Antonello, Rotili, Dante
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177044/ https://www.ncbi.nlm.nih.gov/pubmed/32373514 http://dx.doi.org/10.3389/fonc.2020.00474

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