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Epigenetic Modifications of GABAergic Interneurons Contribute to Deficits in Adult Hippocampus Neurogenesis and Depression-Like Behavior in Prenatally Stressed Mice

BACKGROUND: Prenatal stress (PRS) is considered a risk factor for depressive disorder. Adult hippocampal neurogenesis is believed to play a role in the regulation of affective behaviors. GABAergic interneuron is a key modulator in adult hippocampal neurogenesis. Growing evidence indicates that PRS h...

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Detalles Bibliográficos
Autores principales: Zhong, Haiquan, Rong, Jing, Zhu, Chunting, Liang, Min, Li, Yingchun, Zhou, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177164/
https://www.ncbi.nlm.nih.gov/pubmed/32211762
http://dx.doi.org/10.1093/ijnp/pyaa020