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Intra-Amniotic Delivery of CRMP4 siRNA Improves Mesenchymal Stem Cell Therapy in a Rat Spina Bifida Model

Neural tube defects (NTDs) result in prenatal mortality and lifelong morbidity, and available treatments have limited efficacy. We previously suggested that prenatal bone marrow-derived mesenchymal stem cell (BMSC) transplantation could treat neuron deficiency in NTD rats; however, BMSC-based therap...

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Detalles Bibliográficos
Autores principales: Wei, Xiaowei, Cao, Songying, Ma, Wei, Zhang, Chaonan, Gu, Hui, Liu, Dan, Luo, Wenting, Bai, Yuzuo, Wang, Weilin, Yuan, Zhengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177192/
https://www.ncbi.nlm.nih.gov/pubmed/32330869
http://dx.doi.org/10.1016/j.omtn.2020.03.007