Tie-2 Cre-Mediated Deficiency of Extracellular Signal-Regulated Kinase 2 Potentiates Experimental Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension in Neonatal Mice

Bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension (PH) is a significant lung morbidity of infants, and disrupted lung angiogenesis is a hallmark of this disease. We observed that extracellular signal-regulated kinases (ERK) 1/2 support angiogenesis in vitro, and hyperoxia activates...

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Detalles Bibliográficos
Autores principales: Menon, Renuka T., Shrestha, Amrit Kumar, Barrios, Roberto, Reynolds, Corey, Shivanna, Binoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177249/
https://www.ncbi.nlm.nih.gov/pubmed/32244398
http://dx.doi.org/10.3390/ijms21072408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177249/
https://www.ncbi.nlm.nih.gov/pubmed/32244398
http://dx.doi.org/10.3390/ijms21072408

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