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Pioglitazone-Mediated Peroxisome Proliferator-Activated Receptor γ Activation Aggravates Murine Immune-Mediated Hepatitis

The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) regulates target gene expression upon ligand binding. Apart from its effects on metabolism, PPARγ activity can inhibit the production of pro-inflammatory cytokines by several immune cells, including dendritic cells and mac...

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Detalles Bibliográficos
Autores principales: Schulte, Rike, Wohlleber, Dirk, Unrau, Ludmilla, Geers, Bernd, Metzger, Christina, Erhardt, Annette, Tiegs, Gisa, van Rooijen, Nico, Heukamp, Lukas C., Klotz, Luisa, Knolle, Percy A., Diehl, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177299/
https://www.ncbi.nlm.nih.gov/pubmed/32260486
http://dx.doi.org/10.3390/ijms21072523