Cargando…
Pioglitazone-Mediated Peroxisome Proliferator-Activated Receptor γ Activation Aggravates Murine Immune-Mediated Hepatitis
The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) regulates target gene expression upon ligand binding. Apart from its effects on metabolism, PPARγ activity can inhibit the production of pro-inflammatory cytokines by several immune cells, including dendritic cells and mac...
Autores principales: | Schulte, Rike, Wohlleber, Dirk, Unrau, Ludmilla, Geers, Bernd, Metzger, Christina, Erhardt, Annette, Tiegs, Gisa, van Rooijen, Nico, Heukamp, Lukas C., Klotz, Luisa, Knolle, Percy A., Diehl, Linda |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177299/ https://www.ncbi.nlm.nih.gov/pubmed/32260486 http://dx.doi.org/10.3390/ijms21072523 |
Ejemplares similares
-
Smad7 Deficiency in Myeloid Cells Does Not Affect Liver Injury, Inflammation or Fibrosis after Chronic CCl(4) Exposure in Mice
por: Unrau, Ludmilla, et al.
Publicado: (2021) -
Acute Liver Injury after CCl(4) Administration Is Independent of Smad7 Expression in Myeloid Cells
por: Endig, Jessica, et al.
Publicado: (2019) -
The ADP-Ribosylation Factor 4d Restricts Regulatory T-Cell Induction via Control of IL-2 Availability
por: Geers, Bernd, et al.
Publicado: (2022) -
Pathogenic T-Cell Responses in Immune-Mediated Glomerulonephritis
por: Linke, Alexandra, et al.
Publicado: (2022) -
The PDL1-inducible GTPase Arl4d controls T effector function by limiting IL-2 production
por: Tolksdorf, Felix, et al.
Publicado: (2018)