Low-Dose Phosphodiesterase III Inhibitor Reduces the Vascular Amyloid Burden in Amyloid-β Protein Precursor Transgenic Mice

A previous study reported that relatively high-dose cilostazol (0.3%) promoted the drainage of cerebrovascular amyloid-β (Aβ) protein in Aβ Precursor Protein (APP) transgenic mice overexpressing vasculotropic Aβ. We investigated whether lower-dose cilostazol can decrease micro-hemorrhages and Aβ dep...

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Detalles Bibliográficos
Autores principales: Yakushiji, Yusuke, Kawamoto, Kazuhiro, Uchihashi, Kazuyoshi, Ihara, Masafumi, Aoki, Shigehisa, Nagaishi, Yukiko, Suzuyama, Kohei, Tsugitomi, Yumiko, Hara, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177305/
https://www.ncbi.nlm.nih.gov/pubmed/32225099
http://dx.doi.org/10.3390/ijms21072295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177305/
https://www.ncbi.nlm.nih.gov/pubmed/32225099
http://dx.doi.org/10.3390/ijms21072295

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