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Role of Deubiquitinases in Human Cancers: Potential Targeted Therapy

Deubiquitinases (DUBs) are involved in various cellular functions. They deconjugate ubiquitin (UBQ) from ubiquitylated substrates to regulate their activity and stability. Studies on the roles of deubiquitylation have been conducted in various cancers to identify the carcinogenic roles of DUBs. In t...

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Detalles Bibliográficos
Autores principales: Lai, Keng Po, Chen, Jian, Tse, William Ka Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177317/
https://www.ncbi.nlm.nih.gov/pubmed/32268558
http://dx.doi.org/10.3390/ijms21072548