Molecular T-Cell Repertoire Analysis as Source of Prognostic and Predictive Biomarkers for Checkpoint Blockade Immunotherapy

The T cells are key players of the response to checkpoint blockade immunotherapy (CBI) and monitoring the strength and specificity of antitumor T-cell reactivity remains a crucial but elusive component of precision immunotherapy. The entire assembly of T-cell receptor (TCR) sequences accounts for an...

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Detalles Bibliográficos
Autores principales: Aversa, Ilenia, Malanga, Donatella, Fiume, Giuseppe, Palmieri, Camillo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177412/
https://www.ncbi.nlm.nih.gov/pubmed/32235561
http://dx.doi.org/10.3390/ijms21072378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177412/
https://www.ncbi.nlm.nih.gov/pubmed/32235561
http://dx.doi.org/10.3390/ijms21072378

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