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Molecular T-Cell Repertoire Analysis as Source of Prognostic and Predictive Biomarkers for Checkpoint Blockade Immunotherapy

The T cells are key players of the response to checkpoint blockade immunotherapy (CBI) and monitoring the strength and specificity of antitumor T-cell reactivity remains a crucial but elusive component of precision immunotherapy. The entire assembly of T-cell receptor (TCR) sequences accounts for an...

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Detalles Bibliográficos
Autores principales:	Aversa, Ilenia, Malanga, Donatella, Fiume, Giuseppe, Palmieri, Camillo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177412/ https://www.ncbi.nlm.nih.gov/pubmed/32235561 http://dx.doi.org/10.3390/ijms21072378

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