Combination of Arsenic Trioxide and Valproic Acid Efficiently Inhibits Growth of Lung Cancer Cells via G2/M-Phase Arrest and Apoptotic Cell Death

Arsenic trioxide (ATO; As(2)O(3)) has anti-cancer effects in various solid tumors as well as hematological malignancy. Valproic acid (VPA), which is known to be a histone deacetylase inhibitor, has also anti-cancer properties in several cancer cells including lung cancer cells. Combined treatment of...

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Detalles Bibliográficos
Autores principales: Park, Hyun Kyung, Han, Bo Ram, Park, Woo Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177455/
https://www.ncbi.nlm.nih.gov/pubmed/32290325
http://dx.doi.org/10.3390/ijms21072649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177455/
https://www.ncbi.nlm.nih.gov/pubmed/32290325
http://dx.doi.org/10.3390/ijms21072649

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