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Combination of Arsenic Trioxide and Valproic Acid Efficiently Inhibits Growth of Lung Cancer Cells via G2/M-Phase Arrest and Apoptotic Cell Death
Arsenic trioxide (ATO; As(2)O(3)) has anti-cancer effects in various solid tumors as well as hematological malignancy. Valproic acid (VPA), which is known to be a histone deacetylase inhibitor, has also anti-cancer properties in several cancer cells including lung cancer cells. Combined treatment of...
Autores principales: | Park, Hyun Kyung, Han, Bo Ram, Park, Woo Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177455/ https://www.ncbi.nlm.nih.gov/pubmed/32290325 http://dx.doi.org/10.3390/ijms21072649 |
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