A Peptidomimetic Fluorescent Probe to Detect the Trypsin β2 Subunit of the Human 20S Proteasome

This work describes the chemical synthesis, combinatorial selection, and enzymatic evaluation of peptidomimetic fluorescent substrates specific for the trypsin-like (β2) subunit of the 20S human proteasome. After deconvolution of a library comprising nearly 6000 compounds composed of peg substituted...

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Detalles Bibliográficos
Autores principales: Wysocka, Magdalena, Romanowska, Anita, Gruba, Natalia, Michalska, Michalina, Giełdoń, Artur, Lesner, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177456/
https://www.ncbi.nlm.nih.gov/pubmed/32244300
http://dx.doi.org/10.3390/ijms21072396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177456/
https://www.ncbi.nlm.nih.gov/pubmed/32244300
http://dx.doi.org/10.3390/ijms21072396

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