Combining Molecular Dynamics and Docking Simulations to Develop Targeted Protocols for Performing Optimized Virtual Screening Campaigns on the hTRPM8 Channel

Background: There is an increasing interest in TRPM8 ligands of medicinal interest, the rational design of which can be nowadays supported by structure-based in silico studies based on the recently resolved TRPM8 structures. Methods: The study involves the generation of a reliable hTRPM8 homology mo...

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Detalles Bibliográficos
Autores principales: Talarico, Carmine, Gervasoni, Silvia, Manelfi, Candida, Pedretti, Alessandro, Vistoli, Giulio, Beccari, Andrea R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177470/
https://www.ncbi.nlm.nih.gov/pubmed/32218173
http://dx.doi.org/10.3390/ijms21072265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177470/
https://www.ncbi.nlm.nih.gov/pubmed/32218173
http://dx.doi.org/10.3390/ijms21072265

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