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Keratin Dynamics and Spatial Distribution in Wild-Type and K14 R125P Mutant Cells—A Computational Model

Keratins are one of the most abundant proteins in epithelial cells. They form a cytoskeletal filament network whose structural organization seriously conditions its function. Dynamic keratin particles and aggregates are often observed at the periphery of mutant keratinocytes related to the hereditar...

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Detalles Bibliográficos
Autores principales: Gouveia, Marcos, Zemljič-Jokhadar, Špela, Vidak, Marko, Stojkovič, Biljana, Derganc, Jure, Travasso, Rui, Liovic, Mirjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177522/
https://www.ncbi.nlm.nih.gov/pubmed/32283594
http://dx.doi.org/10.3390/ijms21072596