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Association between Chronic Interstitial Cystitis and Herpes Zoster

Objectives: Herpes zoster (HZ) infection has been associated with disease burdens such as infection and depression. However, the relationship between chronic interstitial cystitis (CIC) and HZ is unknown. This study investigated HZ risk in patients with CIC. Patients and Methods: The Longitudinal He...

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Autores principales: Hsu, Chao-Yu, Lin, Cheng-Li, Kao, Chia-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177600/
https://www.ncbi.nlm.nih.gov/pubmed/32224999
http://dx.doi.org/10.3390/ijerph17072228
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author Hsu, Chao-Yu
Lin, Cheng-Li
Kao, Chia-Hung
author_facet Hsu, Chao-Yu
Lin, Cheng-Li
Kao, Chia-Hung
author_sort Hsu, Chao-Yu
collection PubMed
description Objectives: Herpes zoster (HZ) infection has been associated with disease burdens such as infection and depression. However, the relationship between chronic interstitial cystitis (CIC) and HZ is unknown. This study investigated HZ risk in patients with CIC. Patients and Methods: The Longitudinal Health Insurance Database, which is a subset of the Taiwan National Health Insurance Research Database, was used in the study. The case cohort consisted of patients with newly diagnosed CIC between 2000 and 2012. Each patient with CIC was matched to four controls by age and index year. All participants were traced from the index date to HZ diagnosis, and loss to follow-up or death, or to the end of the study (31 December 2013). Results: A total of 1096 patients with CIC and 4384 controls were enrolled. The incidence rate of HZ in patients with CIC was 10.8 per 1000 person-years, whereas that for controls was 7.25 per 1000 person-years. HZ risk for the case cohort was 1.48 times that for the control cohort. Among participants aged ≤49 years, patients with CIC had a 1.91-fold-increased HZ risk compared to those without CIC. Conclusion: Patients with CIC had a higher risk of HZ than those without CIC. CIC should not be ignored, particularly in young adults.
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spelling pubmed-71776002020-04-28 Association between Chronic Interstitial Cystitis and Herpes Zoster Hsu, Chao-Yu Lin, Cheng-Li Kao, Chia-Hung Int J Environ Res Public Health Article Objectives: Herpes zoster (HZ) infection has been associated with disease burdens such as infection and depression. However, the relationship between chronic interstitial cystitis (CIC) and HZ is unknown. This study investigated HZ risk in patients with CIC. Patients and Methods: The Longitudinal Health Insurance Database, which is a subset of the Taiwan National Health Insurance Research Database, was used in the study. The case cohort consisted of patients with newly diagnosed CIC between 2000 and 2012. Each patient with CIC was matched to four controls by age and index year. All participants were traced from the index date to HZ diagnosis, and loss to follow-up or death, or to the end of the study (31 December 2013). Results: A total of 1096 patients with CIC and 4384 controls were enrolled. The incidence rate of HZ in patients with CIC was 10.8 per 1000 person-years, whereas that for controls was 7.25 per 1000 person-years. HZ risk for the case cohort was 1.48 times that for the control cohort. Among participants aged ≤49 years, patients with CIC had a 1.91-fold-increased HZ risk compared to those without CIC. Conclusion: Patients with CIC had a higher risk of HZ than those without CIC. CIC should not be ignored, particularly in young adults. MDPI 2020-03-26 2020-04 /pmc/articles/PMC7177600/ /pubmed/32224999 http://dx.doi.org/10.3390/ijerph17072228 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hsu, Chao-Yu
Lin, Cheng-Li
Kao, Chia-Hung
Association between Chronic Interstitial Cystitis and Herpes Zoster
title Association between Chronic Interstitial Cystitis and Herpes Zoster
title_full Association between Chronic Interstitial Cystitis and Herpes Zoster
title_fullStr Association between Chronic Interstitial Cystitis and Herpes Zoster
title_full_unstemmed Association between Chronic Interstitial Cystitis and Herpes Zoster
title_short Association between Chronic Interstitial Cystitis and Herpes Zoster
title_sort association between chronic interstitial cystitis and herpes zoster
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177600/
https://www.ncbi.nlm.nih.gov/pubmed/32224999
http://dx.doi.org/10.3390/ijerph17072228
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