Changes of Resurgent Na(+) Currents in the Na(v)1.4 Channel Resulting from an SCN4A Mutation Contributing to Sodium Channel Myotonia

Myotonia congenita (MC) is a rare disorder characterized by stiffness and weakness of the limb and trunk muscles. Mutations in the SCN4A gene encoding the alpha-subunit of the voltage-gated sodium channel Na(v)1.4 have been reported to be responsible for sodium channel myotonia (SCM). The Na(v)1.4 c...

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Detalles Bibliográficos
Autores principales: Huang, Chiung-Wei, Lai, Hsing-Jung, Lin, Pi-Chen, Lee, Ming-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177622/
https://www.ncbi.nlm.nih.gov/pubmed/32276507
http://dx.doi.org/10.3390/ijms21072593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177622/
https://www.ncbi.nlm.nih.gov/pubmed/32276507
http://dx.doi.org/10.3390/ijms21072593

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