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Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunction: Implications for Treating Preeclampsia

In preeclampsia, widespread maternal endothelial dysfunction is often secondary to excessive generation of placental-derived anti-angiogenic factors, including soluble fms-like tyrosine kinase-1 (sFlt-1) and soluble endoglin (sEng), along with proinflammatory cytokines such as tumour necrosis factor...

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Detalles Bibliográficos
Autores principales: Rahman, Rahana Abd, Murthi, Padma, Singh, Harmeet, Gurungsinghe, Seshini, Leaw, Bryan, Mockler, Joanne C., Lim, Rebecca, Wallace, Euan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177667/
https://www.ncbi.nlm.nih.gov/pubmed/32260307
http://dx.doi.org/10.3390/ijms21072504