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Effect of Novel Pyrrolo[3,4-d]pyridazinone Derivatives on Lipopolysaccharide-Induced Neuroinflammation

Neuroinflammation is considered to be one of the potential causes for the development of neurodegenerative diseases, including Alzheimer’s disease. In this study, we evaluated the effect of four newly synthesized pyrrolo[3,4-d]pyridazinone derivatives on the neuron-like PC12 cells under simulated in...

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Detalles Bibliográficos
Autores principales: Wakulik, Karolina, Wiatrak, Benita, Szczukowski, Łukasz, Bodetko, Dorota, Szandruk-Bender, Marta, Dobosz, Agnieszka, Świątek, Piotr, Gąsiorowski, Kazimierz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177677/
https://www.ncbi.nlm.nih.gov/pubmed/32276316
http://dx.doi.org/10.3390/ijms21072575