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A Relatively Small Gradient of Extracellular pH Directs Migration of MDA-MB-231 Cells In Vitro

Hematogenous tumor metastasis begins with the invasion and spread of primary tumor cells in the local tissue leading to intravasation. We hypothesized that tumor cells might actively migrate toward intratumor vessels with the extracellular metabolic gradient acting as a guiding cue. Here, we determi...

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Detalles Bibliográficos
Autores principales: Takahashi, Eiji, Yamaguchi, Daisuke, Yamaoka, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177698/
https://www.ncbi.nlm.nih.gov/pubmed/32272744
http://dx.doi.org/10.3390/ijms21072565