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Female AhR Knockout Mice Develop a Minor Renal Insufficiency in an Adenine-Diet Model of Chronic Kidney Disease

Cardiovascular complications observed in chronic kidney disease (CKD) are associated with aryl hydrocarbon receptor (AhR) activation by tryptophan-derived uremic toxins—mainly indoxyl sulfate (IS). AhR is a ligand-activated transcription factor originally characterized as a receptor of xenobiotics i...

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Detalles Bibliográficos
Autores principales: Makhloufi, Camélia, Nicolas, Fanny, McKay, Nathalie, Fernandez, Samantha, Hache, Guillaume, Garrigue, Philippe, Brunet, Philippe, Guillet, Benjamin, Burtey, Stéphane, Poitevin, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177716/
https://www.ncbi.nlm.nih.gov/pubmed/32260098
http://dx.doi.org/10.3390/ijms21072483