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Female AhR Knockout Mice Develop a Minor Renal Insufficiency in an Adenine-Diet Model of Chronic Kidney Disease
Cardiovascular complications observed in chronic kidney disease (CKD) are associated with aryl hydrocarbon receptor (AhR) activation by tryptophan-derived uremic toxins—mainly indoxyl sulfate (IS). AhR is a ligand-activated transcription factor originally characterized as a receptor of xenobiotics i...
Autores principales: | Makhloufi, Camélia, Nicolas, Fanny, McKay, Nathalie, Fernandez, Samantha, Hache, Guillaume, Garrigue, Philippe, Brunet, Philippe, Guillet, Benjamin, Burtey, Stéphane, Poitevin, Stéphane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177716/ https://www.ncbi.nlm.nih.gov/pubmed/32260098 http://dx.doi.org/10.3390/ijms21072483 |
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