Upregulation of CASP9 through NF-κB and Its Target MiR-1276 Contributed to TNFα-Promoted Apoptosis of Cancer Cells Induced by Doxorubicin

Under some conditions, nuclear factor-κB (NF-κB) has a pro-apoptotic role, but the mechanisms underlying this function remain unclear. This study demonstrated that NF-κB directly binds to CASP9 and miR1276 in tumor necrosis factor α (TNFα)-treated HeLa and HepG2 cells. NF-κB upregulated CASP9 expres...

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Detalles Bibliográficos
Autores principales: Zhou, Fei, Li, Yun, Huang, Yisheng, Wu, Jian, Wu, Qinhan, Zhu, Hui, Wang, Jinke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177739/
https://www.ncbi.nlm.nih.gov/pubmed/32225068
http://dx.doi.org/10.3390/ijms21072290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177739/
https://www.ncbi.nlm.nih.gov/pubmed/32225068
http://dx.doi.org/10.3390/ijms21072290

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