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Suppression of Superficial Microglial Activation by Spinal Cord Stimulation Attenuates Neuropathic Pain Following Sciatic Nerve Injury in Rats

We evaluated the mechanisms underlying the spinal cord stimulation (SCS)-induced analgesic effect on neuropathic pain following spared nerve injury (SNI). On day 3 after SNI, SCS was performed for 6 h by using electrodes paraspinally placed on the L4-S1 spinal cord. The effects of SCS and intraperit...

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Detalles Bibliográficos
Autores principales: Shinoda, Masamichi, Fujita, Satoshi, Sugawara, Shiori, Asano, Sayaka, Koyama, Ryo, Fujiwara, Shintaro, Soma, Kumi, Tamagawa, Takaaki, Matsui, Tomoyuki, Ikutame, Daisuke, Ando, Masatoshi, Osada, Ayaka, Kimura, Yuki, Kobayashi, Kazutaka, Yamamoto, Takamitsu, Kusama-Eguchi, Kuniko, Kobayashi, Masayuki, Hayashi, Yoshinori, Iwata, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177766/
https://www.ncbi.nlm.nih.gov/pubmed/32235682
http://dx.doi.org/10.3390/ijms21072390