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Recombinant Human Plasma Gelsolin Stimulates Phagocytosis while Diminishing Excessive Inflammatory Responses in Mice with Pseudomonas aeruginosa Sepsis

Plasma gelsolin (pGSN) is a highly conserved abundant circulating protein, characterized by diverse immunomodulatory activities including macrophage activation and the ability to neutralize pro-inflammatory molecules produced by the host and pathogen. Using a murine model of Gram-negative sepsis ini...

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Detalles Bibliográficos
Autores principales: Piktel, Ewelina, Wnorowska, Urszula, Cieśluk, Mateusz, Deptuła, Piotr, Prasad, Suhanya V., Król, Grzegorz, Durnaś, Bonita, Namiot, Andrzej, Markiewicz, Karolina H., Niemirowicz-Laskowska, Katarzyna, Wilczewska, Agnieszka Z., Janmey, Paul A., Reszeć, Joanna, Bucki, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177774/
https://www.ncbi.nlm.nih.gov/pubmed/32272559
http://dx.doi.org/10.3390/ijms21072551